XENOVIEW™ Illuminates Distribution of Gas in the Lungs
Traditional magnetic resonance imaging (MRI) scans detect hydrogen nuclei (protons or 1H) found in anatomical structures. However, due to the unique composition of the lungs, it is not common to perform proton-based MRI. XENOVIEW™ MRI scans detect hyperpolarized xenon nuclei inhaled by the patient. The stable, inert xenon isotope exhibits an MRI signal (resonance frequency) that can be detected to determine the distribution of gas in the lungs, allowing clinicians to evaluate regional lung ventilation.
FEV1, forced expiratory volume in one second.
*Example patients from the XENOVIEW™ phase 3 studies. Image shows the distribution intensity of XENOVIEW™ gas. Low to high distribution follows the hot to cold spectrum (red to blue,
respectively). Image processed using XENOVIEW VPD™ software.
XENOVIEW™ Transforms MRI Into a Lung Ventilation Imaging Platform
Not an actual technician.
- Provides direct measurement of regional lung function in patients undergoing evaluation of lung ventilation
- No radiation exposure to patient
- Spatially distributes to image the smallest airways
- Single, 10 to 15 second breath hold
- Non-effort dependent procedure